Effects of ketogenic and western diets on proliferation, vasculogenesis and oxidative stress in the liver

In this study, it was aimed to investigate the effects of different diets on lipid peroxidation, antioxidants, proliferation and vasculogenesis in liver tissue. BALBC female rats (21) were divided as group fed with standard chow (SC), a ketogenic diet (KD) western (WD). The tap water rat specially prepared according determined for 4 weeks. Liver tissue oxidative damage, evaluated using spectrophotometric immunohistopathological methods. At end experiment, found that highest weight gain WD least KD group. mean body statistically significantly higher compared SC groups (p<0.05). MDA levels be lower groups. GSH CAT IHC evaluation results, seen Ki-67 percentage increased (p = 0.000), VEGF close each other all three there no significant difference comparisons between (p>0.05). These results revealed prevents damage by decreasing peroxidation well inducing cellular vasculogenesis.